Scan.
Review laboratory results for disease-specific signatures, including low beta-glucosidase.
Case study · AI patient finding · Gaucher disease
A global biopharmaceutical company used lab results and medical history to flag potential Gaucher patients and support weekly physician follow-up.
Find the pattern across the history
Recurring alerts supported field-team outreach to relevant physicians. Lab-profile matches identified potential patients for further evaluation.
The challenge
Patients may move through years of abnormal lab results before receiving a diagnosis. The pattern can be present across the data while remaining difficult for any single physician to see in full.
The company needed an approach that could review disease-specific signals across laboratory results and medical history, then connect those findings with a physician-outreach workflow.
The approach
The program moved from a review of disease-specific laboratory signatures to clinical profiling and recurring physician alerts.
Review laboratory results for disease-specific signatures, including low beta-glucosidase.
Use laboratory results and medical history to define clinical profiles and flag potential Gaucher patients.
Deliver weekly alerts to support field-team outreach to relevant physicians.
The reported outcome
The source reports an average of one patient per week with low beta-glucosidase during the cited 2025 program periods.
Weekly alerts supported physician follow-up, giving the field team a recurring way to review relevant lab-profile findings.
A profile match is a starting point for further evaluation. It does not confirm a Gaucher diagnosis.
Recurring delivery to support physician outreach
Where else this approach may apply
The source identifies these as potential applications of the approach, rather than additional reported client outcomes.
What the case illustrates
The program used longitudinal clinical information to support patient finding and recurring HCP outreach.
Evaluate lab results with medical history so patient-finding profiles can reflect more than one isolated signal.
Bring potential patient findings into a recurring alert process that supports follow-up with relevant physicians.
Explore patient finding
Talk with Prognos about your rare disease program, relevant laboratory signals, and physician engagement priorities.
Explore lab-informed patient finding and recurring HCP alerts with Prognos.